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TITLE

SPONSOR

PROTOCOL
NUMBER

PRINCIPAL
INVESTIGATOR

BRAIN

A Phase III (Phase I Closed) Randomized Study of Radiation Therapy and Temozolomide (IND# 60, 265) versus Radiation Therapy and BCNU for Anaplastic Astrocytoma and Mixed Anaplastic Oligoastrocytoma (Astrocytoma Dominant)

ECOG

R98-13

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

BREAST (Adjuvant)

Cyclophosphamide and Doxorubicin (CA) (4 vs 6 cycles) Versus Paclitaxel (12 weeks vs 18 weeks) as Adjuvant Therapy for Women with Node-Negative Breast Cancer A 2x2 Factorial Phase III Randomized Study

CALGB

40101

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Randomized Trial of Adjuvant Chemotherapy with Standard Regimens, Cyclophosphamide, Methotrexate and Fluorouracil or Doxorubicin and Cyclophosphamide vs. Capecitabine in Women 65 yrs & Older with Node Positive or High-Risk Node Negative Breast Cancer

CALGB

49907

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Clinical Trial Comparing Anastrozole or Tamoxifen in Postmenopausal Patients with Ductal Carcinoma in SITU (DCIS) Undergoing Lumpectomy with Radiation Therapy

NSABP

B-35

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Phase III, Adjuvant Trial Comparing Three Chemotherapy Regimens in Women With Node-Positive Breast Cancer: Docetaxel/Doxorubicin/Cyclophosphamide (TAC); Dose-Dense (DD) Doxorubicin/Cyclophosphamide Followed by DD Paclitaxel (DD AC -> P); DD AC Followed by DD Paclitaxel Plus Gemcitabine (DD AC -> PG) NSABP B-38 Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930
Phase II Study of Doxil and Carboplatin, plus Herceptin in HER2+Patients, in Metastatic Breast Cancer (MBC) USON 004111 Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

Phase III Trial of Continuous Schedule AC + G Vs. Q 2 Week Schedule AC, Followed by Paclitaxel Given Either Every 2 Weeks or Weekly for 12 Weeks as Post-Operative Adjuvant Therapy in Node-Positive or High-Risk Node Negative Breast Cancer

SWOG

0221

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

BREAST (Metastatic)

An Open-label Randomized Phase II Study of Two Different Dosing Regimens of Capecitabine in Combination with Intravenous Docetaxel (Q3W) In Patients with Locally Advanced and/or Metastatic Breast Cancer

Roche

NO16853B

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

Randomized Phase II Study of Weekly Irinotecan/Carboplatin (ICb) with or without Cetuximab (Erbitux) in Patients with Metastatic Breast Cancer

USON

04070

Ira A. Oliff, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

GASTROINTESTINAL (Colon/Rectal)

PACCE: A Randomized, Open-Label, Controlled, Clinical Trial of Chemotherapy and Bevacizumab With and Without Panitumumab in the First-line Treatment of Subjects With Metastatic Colorectal Cancer

AMGEN

20040249

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Randomized Phase III Trial of Irinotecan (CPT-11) and/or Oxaliplatin (OXAL) Plus 5-Fluorouracil (5-FU)/Leucovorin (CF) with or without Cetuximab (C225) after Curative Resection for Patients with Stage III Colon Cancer

CTSU/NCCTG

N0147

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Randomized Phase III Study Comparing 5-FU, Leucovorin and Oxaliplatin vs. 5-FU, Leucovorin, Oxaliplatin, and Bevacizumabin Pts. With Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers

ECOG

5202

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

Phase II Study of Treatment Selection Based Upon Tumor Thymidylate Synthase Expression in Previously Untreated Patients with Metastatic Colorectal Cancer

ECOG

4203

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

Chemoembolization in Hepatocellular Carcinoma or Neuroendocrine Hepatic Metastases: A Phase II Multi-Center Trial

ECOG

E4298

Ira A. Oliff, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

"XELOX-A-DVS" (Dense Vs Standard): A Randomized Study of Intermittent Capecitabine in Combination with Oxaliplatin (XELOX Q3W) and Bevacizumab versus Intermittent Capecitabine in Combination with Oxaliplatin (XELOX Q2W) and Bevacizumab as First-Line Treatment for Patients with Metastatic Colorectal Cancer (ML18491)

USON

05003

Ira A. Oliff, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

GASTROINTESTINAL (Gastric)

A Phase III Trial of Adjuvant Chemoradiation after Resection of Gastric and Gastroesophageal Adenocarcinoma CALGB 80101 Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Phase II Study to Evaluate Overall Response Rate of BAY 43-9006 (Sorafenib) Combined with Docetaxel and Cisplatin in the Treatment of Metastatic or Advanced Unresectable Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma

ECOG

5203

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

GASTROINTESTINAL (Hepatic)

A Phase II Trial of Bortezomib Plus Doxorubicin in Hepatocellular Carcinoma ECOG 6202 Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax). Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

Chemoembolization in Hepatocellular Carcinoma or Neuroendocrine Hepatic Metastases: A Phase II Multi-Center Trial

ECOG

4298

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

 

GASTROINTESTINAL (Pancreatic)

A Randomized, Open-Label Phase 2 Studyt of 2 Regimens, Gemcitabine plus Enzastaurin and Single-Agent Gemcitabine, in Patients with Locally Advanced or Metastatic Pancreatic Cancer USON 05044 Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Phase 2 Trial of Irinotecan/Docetaxel for Adv. Pancreatic Cancer, with Randomization between Irinotecan/Docetaxel & Irinotecan/Docetaxel Plus C225 a Monoclonal Antibody to the Epidermal Growth Factor Receptor. This study is suspended to accrual

ECOG

8200

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

GASTROINTESTINAL (Rectal)

Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil and Leucovorin vs Oxaliplatin, 5-Fluorouracil, Leucovorin and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Pre-operative Chemoradiation ECOG 5204 Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Clinical Trial Comparing Preop Radiation and Xeloda with/without Oxaliplatin with preop radiation and continuous IV of 5 FU with/without Oxaliplatin in the tx of pts. With operable carcinoma of the rectum

NSABP R-04 Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

ENDOMETRIAL

No Current Trials

     

ESOPHAGEAL

No Current Trials

     

GENITOURINARY (Bladder)

A Phase II Random. Trial for Pts. With Ms. Invading Bladder Ca. Evanluat. Transurethral Surgery and BID Irradiation Plus either Paclitaxel and Cisplatin or 5-FU and Cisplatin Followed by Selective Bladder Preservation and Gemcitabine/Paclitaxel/Cispl.Adj

RTOG

0223

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

GENITOURINARY (Prostate)

Intermittent Androgen Deprivation in Patients with Stage D2 Prostate Cancer, Phase III

ECOG

S9346

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Phase II Study of PROSTV AC-V (Vaccinia)/TRICOM and PROSTV AC-F (Fowlpox)/TRICOM with GM-CSF in Patients with PSA Progression After Local Therapy for Prostate Cancer

ECOG

9802

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

GENITOURINARY (Renal)

A Randomized, Double-Blind Phase III Trial of Adjuvant Sunitnib versus Sorafenib versus Placebo in Patients with Resected Renal Cell Carincoma ECOG 2805 Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

Phase II Trial of Doxorubicin and Gemcitabine in Metastatic Renal Cell Carcinoma with Sarcomatoid Features

ECOG

8802

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

Phase II Trial of Paclitaxel Plus Carboplatin in Patients with Metastatic or Locally Advanced Collecting Duct Renal Cell Cancer

ECOG

2803

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

HEAD & NECK (Advanced)

Phase II of PS-341 (NSC 681239) Followed by the Addition of Doxorubicin at Progression in Advanced Adenoid Cystic Carcinoma of the Head and Neck SUSPENDED

ECOG

1303

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

Phase III Randomized, Placebo Controlled, Trial of Docetaxel Versus Docetaxel Plus ZD1839 (Iressa, Gefitinib) in Performance Status 2 or Previously Treated Patients with Recurrent or Metastatic Head and Neck Cancer

ECOG

1302

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

LEUKEMIA (ALL)

Phase III Randomized Trial of Autologous and Allogeneic Bone Marrow Transplantation Versus Intensive Conventional Chemotherapy in Acute Lymphoblastic Leukemia in First Remission.

ECOG

2993

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

LEUKEMIA (AML)

A Phase III Randomized Study of Farnesyl Transferase Inhibitor R115777 in Acute Myeloid Leukemia (AML) Patients in Second or Subsequent Remission or in Remission after Primary Induction Failure

ECOG

2902

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Phase III Trial in Adult Acute Myeloid Leukemia: Daunorubicin Dose-Intensification and Gemtuzumab-Ozogamicin Consolidation Therapy prior to Autologous Stem Cell Transplantation

ECOG

1900

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

LEUKEMIA (CLL)

Phase II Trial of Pentostatin, Cyclophosphamide and Rituximab (PCR) Followed By Campath-1H For Previously Treated Relapsed or Refractory Patients With Chronic Lymphocytic Lymphoma

ECOG

2903

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

LEUKEMIA (CML)

A Phase IIb Study of Molecular Responses to Imatinib at Standard or Increased Doses for Previously Untreated Patients with Chronic Myelogenous Leukemia (CML) in Chronic Phase

ECOG

S0325

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

LEUKEMIA (Laboratory)

Ancillary Laboratory Protocol for Collecting Diagnostic Material on Patients Considered for ECOG Treatment Trials for Leukemia or Related Hematologic Disorders

ECOG

3903

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

LEUKEMIA (Miscellaneous)

A Phase II Study of Initial Treatment with Methotrexate in Large Granular Lymphocytic (LGL) Leukemia

ECOG

5998

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A prospective, randomized, open label, phase III trial of fludarabine, cyclophosphamide, and rituximab vs. pentostatin, cyclophosphamide, and rituximab in previously untreated or treated b-cell chronic lymphocytic leukemia

USON

03017

Ira A. Oliff, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

LUNG (Non Small Cell)

A Randomized Multicenter Phase II Study of Taxane/Carbo/Cetuximab versus Taxane/Carbo as First-Line treatment for Patients with Advanced/Metastatic Non-Small Cell Lung Cancer

BMS

CA22599

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Randomized, Open-Label Phase II Study of Pemetrexed (Alimta) plus Carboplatin with or without Enzastaurin Hydrochloride, or Docetaxel plus Carboplatin as First Line Treatment in Patients with Advanced Stage Non-Small Cell Lung Cancer (NSCLC) USON 05082 Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Phase III Trial of Carboplatin, Paclitaxel and Thoracic Radiotherapy With or Without Thalidomide, in Patients with Stage III NSCLC

ECOG

3598

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Double Blind Phase II Study of BAY-43-9006 in Patients with Non-Small Cell Lung Cancer who have Failed at Least Two Prior Chemotherapy Regimens

ECOG

2501

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Phase II Trial of Induction Chemoradiotherapy with Cisplatin/Etoposide Followed by Surgical Resection, Followed by Docetaxel, for Non-Small Cell Lung Cancer Involving the Superior Sulcus (Pancoast Tumors)

ECOG

S0220

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

BETA: Phase III / Double-Blind / Placebo-Controlled Trial of Bevacizumab in Combination with Tarceva Compared with Tarceva Alone for Treatment of Advanced Non-Small Cell Lung Cancer After Failure of Standard First Line Chemo

Genentech
/OSI

OSI3364g

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

Molecular Profiling of Non-Small cell Lung Cancer with Clinical Correlations

Rush

LUNG TISSUE

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Randomized Controlled Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel plus or minus Sorafenib (BAY 43-9006) in chemonaive patients with Stage IIIB-IV non-small cell lung cancer

BAYER

11961

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

LUNG (NSCLC)

Phase III Chemoprevention Trial of Selenium Supplementation in Persons with Resected Stage I Non-Small Cell Lung Cancer

ECOG

5597

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Randomized Trial of Carboplatin/Gemcitabine vs. Gemcitabine alone in PS2 Patients with Advanced (Stage IIIB or IV) NSCLC

USON

03012

Ira A. Oliff, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

LUNG (Laboratory)

Molecular Epidemiology Case-Series Study of Non-Small Cell Lung Cancer in Smoking and Non-Smoking Women and Men

SWOG

0424

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

LUNG (Thymoma)

Phase II Study of Carboplatin plus Paclitaxel Treatment of Advanced Thymoma or Thymic Carcinoma

ECOG

1C99

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

LYMPHOMA (Hodgkins)

 

 

 

 

LYMPHOMA (Non Hodgkins)

A Phase II Study of Cyclosporine in the Treatment of Angioimmunoblastic T-Cell LymphomaA Phase II Study of Cyclosporine in the Treatment of Angioimmunoblastic T-Cell Lymphoma

ECOG

2402

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Randomized Phase III Trial of Rituximab (NSC #687451) and Autologous Stem Cell Transplantation for B Cell Diffuse Large Call Lymphoma

ECOG

2499

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

Early High Dose Chemoradiotherapy and ASCT to Conventional Dose CHOP Chemotherapy (with possible Late ASCT) for Patients with Diffuse, Aggressive NHL

ECOG

S9704

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

Randomized Phase III Trial Comparing Two Different Rituximab Dosing Regimens for Low Tumor Burden Patients with Indolent Non-Hodgkin's Lymphoma

ECOG

4402

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Phase II Trial of R-CHOP Followed By Zevalin Radioimmunotherapy for Patients with Previously Untreated Stages I and II CD20+ Diffuse Large Cell Non-Hodgkin's Lymphoma

ECOG

3402

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

A Randomized Phase II Trial of Outpatient Immunotherapy with Rituximab and Aldesleukin (IL-2) vs. Rituximab Alone for CD20 Positive Aggressive Non-Hodgkin's Lymphoma Following High Dose Therapy with Autologous PBSC Rescue

USON

04099

Ira A. Oliff, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

MELANOMA (High Risk)

Randomized Study of Four Weeks High Dose Interferon Alpha-2b in Stage IIa Melanoma

ECOG

E1697

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

Yeast Derived GM-CSF Versus Peptide Vaccination Vs. GM-CSF Plus Peptide Vaccination Versus Placebo in Patients with "No Evidence of Disease" After Complete Surgical Resection of "Locally Advanced" and/or Stage IV Melanoma

ECOG

4697

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

Phase III Trial of High Dose Interferon Alpha-2b Versus Cisplatin, Vinblastine, DTIC Plus IL-2 and Interferon in Patients with High Risk Melanoma

ECOG

S0008

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

MELANOMA (Metastatic)

Phase II Study of Low Dose Peginterferon Alfa-2b in Patients with Metastatic Melanoma Over-Expressing Basic Fibroblast Growth Factor

ECOG

2602

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax).Ira A. Oliff, M.D., Susan Brown, M.D., Teresa Law, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

A Randomized Phase II Trial of Multi-epitope Vaccination with Melanoma Peptides for Cytotoxic T cells and Helper T cells for Patients with Metastatic Melanoma

ECOG

1602

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

MESOTHELIOMA

No Current Trials

 

 

 

MULTIPLE MYELOMA

A Phase II Open-label Trial of Velcade in Velcade-naive Patients with Multiple Myeloma who have undergone High-dose Melphalan Therapy followed by Autologous Peripheral Blood Stem Cell Transplantation and Failed to Achieve a Complete Response

USON

03047

Ira A. Oliff, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

MYELODYPLASTIC SYNDROME

No Current Trials

 

 

 

OVARIAN

Phase III Randomized Trial of Induction Chemotherapy with Gemcitabine and Carboplatin Followed by elective Paclitaxel Consolidation versus Paclitaxel and Carboplatin Followed by elective Paclitaxel Consolidation in Patients with Primary Epithelial Ovarian, Primary Peritoneal Cancer or Fallopian tube Carcinoma (D) (B9E-US-S302)

USON

02044

Ira A. Oliff, M.D.
9711 Skokie Blvd,
Ste A
Skokie, IL 60076
847-568-9930

SARCOMA

A Phase III Randomized Double-blind Study of Adjuvant STI571 (Gleevec) Versus Placebo in Patients Following the Resection of Primary GastroIntestinal Stromal Tumor (GIST) (ECOG endorsed / CTSU)

ACOSOG

Z9001

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

 

 

 

 

TESTICULAR

No Current Trials

 

 

 

MISCELLANEOUS

ECOG Laboratory Study: Mapping Interactive Cancer Susceptibility Loci

ECOG

E1Y97

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

MISCELLANEOUS (Anemia)

 

 

 

 

MISCELLANEOUS (Catheter Occlusion)

SONOMA 2: Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Alfimeprase in Subjects with Occluded Central Venous Access Devices

Nuvelo

HA006

Edward Kaplan, M.D., Marlon Kleinman, M.D.
9631 Gross Point Rd.
Suite 10
Skokie, IL 60076
847.675.3900 (phone)
847.675.3930 (fax)

GENETIC COUNSELING
DIAGNOSTICS
SURGERY
IMAGING AND RADIATION THERAPY
CHEMOTHERAPY
PALLIATIVE CARE AND SUPPORT
RESEARCH